Asad Mirza

Assistant Research Professor, Florida International University

Department of Biomedical Engineering
10555 West Flagler Street
Miami, FL, 33174, USA

Academic Email - amirza@fiu.edu
Work Email - asadmirza33165@gmail.com

Education

Aug 2018 - June 2024 Ph.D., Biomedical Engineering, Florida International University, Miami, FL, USA.
GPA: 3.84/4.0
Thesis:“Computational Model for Aortic Valve Calcification Prediction Through Hemodynamic Biomarkers”

Aug 2014 - Dec 2017 B.S., Biomedical Engineering, Florida International University, Miami, FL, USA.
GPA: 3.74/4.0
Senior Design Project:“A System for Wholefield Fluorescent Microscopy Imaging In-Vivo”

Work Experience

Aug 2024 - Present Assistant Research Professor, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Dr. Tsoukias’s Vascular Physiology and Biotransport
Dr. Hutcheson’s Cardiovascular Matrix Remodeling Lab
Vida Engineering LLC

Aug 2019 - June 2024 Lab Assistant, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Dr. Ramaswamy’s Cardiovascular Therapeutics Lab
CAVD Hemodynamic Biomarker Project

Oct 2017 - Dec 2017 BME Department Tutor, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
BME 2740: Modeling and Simulation
BME 4100: Biomaterials

Jan 2016 - Aug 2019 Lab Assistant, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Dr. Tsoukias’s Vascular Physiology and Biotransport Lab
Pericyte cell modeling

Aug 2014 - Aug 2018 CHEMPAL Tutor, Department of Chemistry, Florida International University, Miami, FL, USA.

Jan 2017 - April 2017 Teaching Assistant, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
BME 2740: Modeling and Simulation

Aug 2015 - Jan 2017 Professional Tutor, Beck College Prep, Miami, FL, USA.
ACT/SAT/SAT Subject Test Tutor

Jan 2015 - Jun 2017 Graphics Design Intern, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.

Sep 2014 - Jan 2015 Social Media Head, NextGen Climate - Miami Sector, Miami, FL, USA.

Sep 2014 - Mar 2015 General Tutor, Little Lighthouse Foundation, Miami, FL, USA.

Aug 2014 - Apr 2015 Tutor, Southwest Miami Senior High School, Miami, FL, USA.
AP Physics / AP Chemistry

Aug 2010 - Apr 2014 Hospital Volunteer, Nicklaus Children’s Hospital (formally Miami Children’s Hospital), Miami, FL, USA.
Child Care, Activity Cart, In-Patient Pharmacy

Publications

Publication list also available on Google Scholar.

Journal Articles

2024 Mirza A, Hsu C-PD, Rodriguez A, Alvarez P, Lou L, Sey M, Agarwal A, Hutcheson JD, Ramaswamy S. “Computational Model for Early-Stage Aortic Valve Calcification Shows Hemodynamic Biomarkers” Bioengineering, 2024 (Under Review)

2024 Xiao, Z, Mirza A, et al., “A Bypass Flow Model to Study Endothelial Cell Mechanotransduction Across Diverse Flow Environments. Materials Today Bio” 2024: p. 101121. https://doi.org/10.1016/j.mtbio.2024.101121

2022 Gonzalez, B.A; Herrera, A; Ponce, C; Gonzalez Perez, M; Hsu, C.-P.D; Mirza, A; Perez, M; Ramaswamy, S. “Stem Cell-Secreted Allogeneic Elastin-Rich Matrix with Subsequent Decellularization for the Treatment of Critical Valve Diseases in the Young” Bioengineering 2022, 9, 587. https://doi.org/10.3390/bioengineering9100587

2022 Hsu C-PD, Tchir A, Mirza A, Chaparro D, Herrera RE, Hutcheson JD, Ramaswamy S. “Valve Endothelial Cell Exposure to High Levels of Flow Oscillations Exacerbates Valve Interstitial Cell Calcification” Bioengineering [10.3390/bioengineering9080393] https://doi.org/10.3390/bioengineering9080393, 2022

2022 Mirza A, Ramaswamy S. “Importance of Non-Newtonian Computational Fluid Modeling on Severely Calcified Aortic Valve Geometries-Insights from Quasi-Steady State Simulations” Journal of Biomechanical Engineering.doi: 10.1115/1.4054630, 2022

2020 Gonzalez B, Perez-Nevarez M, Mirza AM, Perez M, Ramaswamy S. “Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype” Frontiers in Cardiovascular Medicine.doi: 10.3389/fcvm.2020.00069, 2020, Co-First Author

2019 Mozneb M, Mirza AM, Li CZ. “Non-Invasive Plasmonic Based Real Time Characterization of Cardiac Drugs on Cardiomyocytes Functional Behavior”. Analytical Chemistry. doi: 10.1021/acs.analchem.9b04956, 2019

2019 Tesfamariam MD, Mirza AM, Chaparro D, et al. “Elastin-Dependent Aortic Heart Valve Leaflet Curvature Changes During Cyclic Flexure”. Bioengineering (Basel). doi: 10.3390/bioengineering6020039, 2019

2018 Mirza AM, Moshkforoush A, Tsoukias N, “Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell”, 2018 (In Preparation) .

Conference Abstracts

2021 CPD Hsu, Mirza A, Matheny R, Ramaswamy S. “Tricuspid Versus Mitral Performance of Cylindrical Porcine Small Intestinal Submucosa Valves” Structural Heart. doi: 10.1080/24748706.2021.1900706, 2021

2021 Barreto A, Paolino L, Orikasa-Lopez K, Mirza A, Agarwal A, Hutcheson J, Ramaswamy S. “Constitutive Properties of Mitral Valve Tissues via Nanoindentation” Structural Heart. doi: 10.1080/24748706.2021.1901492, 2021

2021 Mirza A, Barreto A, Boodooram T, Ramaswamy S. “Importance of Non-Newtonian Modeling of Blood Flow for Calcified Aortic Valves: Relevance to Sub-Clinical Thrombosis” Structural Heart. doi: 10.1080/24748706.2021.1901539, 2021

2020 Gonzalez B, Perez M, Mirza A, Scholl F, Bibevski S, Wagner K, Bibevski J, Hernandez L, Ladich E, Brehier V, Casares M, Morales P, Lopez J, Wagner J, Ramaswamy S. “Extracellular Matrix Quantification of Fully Regenerated Neochorade After Bio-scaffold Mitral Valve Implantation in a Juvenile Non-human Primate Model” Circulation. doi: 10.1161/circ.142.suppl_3.14888, 2020

2020 CPD Hsu, Mirza A, Ramaswamy S. “Hydrodynamic Assessment of a Small Intestinal Submucosa Tubular Aortic Valve” Structrual Heart. doi: 10.1080/24748706.2020.1717270, 2020

2020 Mirza A, CPD Hsu, Ramaswamy S. “Hydrodynamic Assessment of a Small Intestinal Submucosa Tubular Mitral Valve” Structrual Heart. doi: 10.1080/24748706.2020.1717272, 2020

2019 Ashenagar B, Moshkforoush A, Mirza A, Tsoukias N. “Integrative Modeling of Functional Hyperemia: From Ion Channel Activity to Functional Imaging” The FASEB Journal. doi: 10.1096/fasebj.2019.33.1_supplement.684.3, 2019

2019 Mirza A, Moshkforoush A, Giles W, Tsoukias N. “A Mathematical Model of Plasma Membrane Electrophysiology of a Brain Capillary Pericyte: Investigating Pericyte Contribution to the Electrical Properties of the Capillary Network” The FASEB Journal. doi: 10.1096/fasebj.2018.32.1_supplement.712.10, 2019

Grants, Fellowships, and Funding

Fellowships

Aug 2023 DYF 2023 Fellowship, University Graduate School, USA, $17,000.

Dec 2020 KFF 2021 Fellowship, Koerner Family Foundation, USA, $10,000.

Jun 2017 McNair Undergraduate Fellowship, Ronald E. McNair Post-Baccalaureate Achievement Program, USA, $1,000.

Grants

Jan 2023 SGA Graduate Scholarship, SGA, USA, $1,000.

Oct 2017 Braman Scholars Completion Grant, Braman Family Foundation, USA, $1,000.

Awards and honors

Feb 2024 Oral Competition 1st Place Winner, Graduate Research Day 2024, Miami, FL

Feb 2024 Poster Competition 1st Place Winner, Heart Day 2024, Miami, FL

Dec 2022 SGA Graduate Scholarship, SGA, Florida International University, Miami, FL.

Feb 2022 Poster Competition 2nd Place Winner, Heart Day 2022, Miami, FL

Sep 2018 Trainee Poster Award Winner, 11th World Congress for Microcirculation, Vancouver, CA.

Dec 2017 2nd Place Oral Presentation, Fall 2017 Senior Design Competition, FIU Biomedical Engineering Department, Miami, FL.
“System for Wholefield Fluroscent Microscopy Imaging In-Vivo”

Apr 2017 McNair Scholar, Ronald E. McNair Postbaccalaureate Achievement Program Scholar, Miami, FL.
14th Cohort

Dec 2015 SGA Resident Scholarship, SGA, Florida International University, Miami, FL.

Aug 2014 - Dec 2017 FIU Dean’s List, Florida International University, Miami, FL.

Aug 2014 FIU Presidential Scholarship, Florida International University, Miami, FL.

Apr 2014 2nd Place Vex Robotics Competition, Florida Division, Southwest Miami Senior High School, Miami, FL.

Conference Proceedings

Oral Presentations

Feb 2024

Mirza A, Ramaswamy S: Fluid-Structure-Interaction Models of Early-Stage Calcified Aortic Valves Show Hemodynamics Biomarkers. Graduate Research Day 2024, Florida International University, Miami, FL

Mar 2023

Mirza A, Ramaswamy S: Development of a Patient-Specific Parameterized Aortic Heart Valve Computational Model. Graduate Research Day 2023, Florida International University, Miami, FL

April 2021 Mirza AM, Barreto A, Boodooram T, Ramaswamy S (Pre-recorded): Importance of Non-Newtonian Modeling of Blood Flow for Calcified Aortic Valves, Heart Vale Society (HVS) Annual Meeting 2021, Virtual Meeting, April 9th, 2021.

June 2020 Mirza AM, Barreto A, Ramaswamy S (Pre-recorded): The Effect of Pulsatility on Thrombus Risk in Trans-Aortic Stent Geometries, 2020 Summer Biomechanics, Bioengineering, and Biotransport Conference (SB3C), Virtual Meeting, June 17-20, 2020.

Feb 2020 Hsu C-PD, Mirza A, Matheny R, Ramaswamy S:Hydrodynamic Assessment of a Small Intestinal Submucosa Tubular Mitral Valve, 2nd International Conference of Tissue-Engineered Heart Valves (ICTEHV), satellite meeting as part of the Heart Valve Society (HVS) Annual Meeting 2020 February 14-16,Abu Dhabi, UAE, 2020.

Sep 2018 Moshkforoush A, Mirza A, Longden T, Dabertrand F, Harraz O, Nelson M, Tsoukias N: Requirements for regenerative conduction of hyperpolarization in cerebral capillaries: a model analysis. World Congress for Microcirculation 2018, Vancouver, CA, Oct 9-13.

Dec 2017 Mirza A, Robledo E, Pinzon J, Fuenzalida N: System for Whole Field Fluorescence Microscopy Imaging In-Vivo. BME Senior Design Project, Florida International University, Miami, FL

Oct 2017 Mirza A, Moshkforoush A, Giles W,Tsoukias N: Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell. 2017 FIU McNair’s Scholars Research Conference, Florida International University, Miami, FL

Poster Presentations

Oct 2023 Mirza A, Ramaswamy S: Computational Reproduction of the Aortic Valve Geometry for Patient-Specific Simulations. Biomedical Engineering Society Annual Fall Meeting (BMES), October 11-14, Seattle, WA, 2023.

March 2023 Mirza A, Ramaswamy S: Towards the Creation of a Parameterized Asymmetric Aortic Valve Model. GSAW Scholarly Forum 2023, Florida International University, Miami, FL

Feb 2023 Mirza A, Ramaswamy S: Towards the Creation of a Parameterized Asymmetric Aortic Valve Model. Miami Heart Day 2023, Florida International University, Miami, FL

Apr 2022 Mirza A, Ramaswamy S: Preliminary FSI Model of a Healthy Vs Severely Calcified Aortic Valve. GSAW Scholarly Forum 2022, Florida International University, Miami, FL

Mar 2022 Perez M, Gonzalez B, L Yih-Mei, Mirza A, Ramaswamy S: Oscillatory Flow Conditioned Exosomes for the Treatment of Myocardial Infarction. Graduate Research Day 2022, Florida International University, Miami, FL

Mar 2022 Mirza A, Ramaswamy S: Preliminary FSI Model of a Healthy Vs Severely Calcified Aortic Valve. Graduate Research Day 2022, Florida International University, Miami, FL

Mar 2022 Mirza A, Ramaswamy S: Need For A More Representative Constitutive Model For Severely Calcified Aortic Valves. Heart Valve Society (HVS) Annual Meeting 2022, Nobu Hotel, Miami, FL

Feb 2022 Perez M, Gonzalez B, L Yih-Mei, Mirza A, Ramaswamy S: Enhanced Stem Cell Exosome Production Under Oscillatory Flow. Miami Heart Day 2022, Florida International University, Miami, FL

Feb 2022 Mirza A, Ramaswamy S: Discrepancies Between Material Models Used for Severely Calcified Aortic Valves. Miami Heart Day 2022, Florida International University, Miami, FL

March 2021 Mirza AM, Barreto A, Boodooram T, Ramaswamy S: Enhanced Hemodynamics Predictions in a Calcified Aortic Valve Geometry Using the Quemada Model, Graudate Research Day 2021, Florida International University (Virtual), Miami, FL

Mar 2020 Mirza A, Barreto A, Ramaswamy S: The Effect of Pulsatility on Thombus Risk in Trans-Aortic Stent Geometries. Graudate Research Day 2020, Florida International University, Miami, FL

Feb 2020 Mirza A, Barreto A, Ramaswamy S: The Effect of Pulsatility on Thombus Risk in Trans-Aortic Stent Geometries. Miami Heart Day 2020, Florida International University, Miami, FL

Oct 2019 Mirza A, Barreto A, Ramaswamy S: Aortic Valve Shape Assessment Following Elastin Degradation. Biomedical Engineering Society Annual Fall Meeting (BMES), October 16-19, Philadelphia, PA, 2019.

June 2019 Barreto AD, Mirza AM, Ramaswamy S: A Spatial Mean Curvature Map of the Aortic Valve -Relevance to Calcification. SB3C2019, Summer Biomechanics, Bioengineering and Biotransport Conference,June 21 –24, Seven Springs, June 25-28, PA, 2019.

Mar 2019 Mirza A, Barreto A, Ramaswamy S: Axial Curvature Evaluation in Aortic Valve Tissue-Strips Following Elastin Degradation. Graduate Research Day 2019, Florida International University, Miami, FL

Feb 2019 Mirza A, Barreto A, Ramaswamy S: Axial Curvature Evaluation in Aortic Valve Tissue-Strips Following Elastin Degradation. Miami Heart Day 2019, Florida International University, Miami, FL

Oct 2018 Mirza A, Moshkforoush A, Nelson M, Tsoukias N: Multiscale Modeling of Cerebral Blood Flow: From Neurovascular Coupling to Tissue Perfusion and Oxygenation. BMES 2018, Atlanta, GA

Sep 2018 Moshkforoush A, Mirza A, Longden T, Dabertrand F, Harraz O, Nelson M, Tsoukias N: Requirements for regenerative conduction of hyperpolarization in cerebral capillaries: a model analysis. World Congress for Microcirculation 2018, Vancouver, CA, Sep 9-13.

Sep 2018 Mirza A, Moshkforoush A, Nelson M, Tsoukias N: Multiscale Modeling of neurovascular Coupling: From Ion Channel Activity to BOLD fMRI Responses. World Congress for Microcirculation 2018, Vancouver, CA, Sep 9-13.

Apr 2018 Mirza A, Moshkforoush A, Giles W, Tsoukias N: A Mathematical Model of Plasma Membrane Electrophysiology of a Brain Capillary Pericyte: Investigating Pericyte Contribution to the Electrical Properties of the Capillary Network. Experimental Biology 2018, San Diego, CA, USA

Oct 2017 Mirza A, Moshkforoush A, Giles W, Tsoukias N: Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell. 8th Annual BME Undergraduate Research Day, Florida International University, Miami, FL

Sep 2017 Mirza A, Moshkforoush A, Giles W, Tsoukias N: Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell. 10th Annual Nanoscience Technology Symposium, Florida International University, Miami, FL

Jul 2017 Mirza A, Moshkforoush A, Giles W, Tsoukias N: Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell. 2017 University of Buffalo (UB) Undergraduate Research Conference, University of Buffalo, Buffalo, NY, USA

Apr 2017 Mirza A, Blanco V, Kirk P, Garcia L, Jung R: Evidence of PAC During Preksha Meditation. 2017 Biophysics of Neural Computation Research Conference, Florida International University, Miami, FL

Mar 2017 Mirza A, Moshkforoush A, Giles W, Tsoukias N: Mathematical Model of Plasma Membrane Electrophysiology in a Single Pericyte Cell. 7th Annual BME Undergraduate Research Day, Florida International University, Miami, FL

Teaching

Guest Lectures

2023 Image Processing, Department of Biomedical Engineering, Florida International University, Miami, FL, USA

2023 MATLAB Basics, Department of Biomedical Engineering, Florida International University, Miami, FL, USA

2021 ANSYS CFD, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2021 ANSYS FEA, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 MATLAB Data Presentation, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 Image Processing Part 2, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 Image Processing Part 1, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 MATLAB Basics Part 3, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 MATLAB Basics Part 2, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 MATLAB Basics Part 1, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 3D Printing, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

2020 GUI Development, Department of Biomedical Engineering, Florida International University (Virtual), Miami, FL, USA

Graduate Assistant Teaching

Spring 2023

Fall 2022

Spring 2022

Fall 2021

Fall 2021

Summer 2020

Spring 2020

Winter 2020

Fall 2020

Fall 2020

Spring 2020

Fall 2019

Summer 2019

Spring 2019

Fall 2018

Spring 2018

Supervision


Senior Design Group Consultation

Fall 2022

Fall 2021

Fall 2020

Spring 2020

Fall 2019

Spring 2019

Spring 2018

Fall 2017

Undergraduate Interns

2020-2021 Tisha Boodooram, Biomedical Engineering Department, Florida International Unvierstiy, Miami, FL.

2018-2021 Amanda Barreto, Biomedical Engineering Department, Florida International Unvierstiy, Miami, FL.

2019 Sergio Rodriguez, Biomedical Engineering Department, Florida International Unvierstiy, Miami, FL.

Professional Training

2017 Six Sigma - Yellow Belt, Florida International University, Miami, FL, USA.
The Six Sigma Yellow Belt certification is aimed at those new to the world of Six Sigma who have a small role, interest, or need to develop foundational knowledge.

University Service

Summer 2024 20240 Summer BME Senior Design Oral Judge, Biomedical Engineering Society, Florida International University, Miami, FL, USA

Fall 2020 2020 Fall BME Senior Design Poster Judge, Biomedical Engineering Society, Florida International University, Miami, FL, USA

Spring 2020 2020 Spring BME Senior Design Poster Judge, Biomedical Engineering Society, Florida International University, Miami, FL, USA

Fall 2019 2019 Fall BME Senior Design Poster Judge, Biomedical Engineering Society, Florida International University, Miami, FL, USA

Community Outreach

2019 EMBS BME Presentation - 3D Printing and Simulation, Pinecrest Cove Preparatory Academy, Miami, FL, USA.
Taught middle school students about 3D printing and BME oriented simulations (hip implants, computer cooling, etc)

2017 Guest lecture, Southwest Miami Senior High School, Miami, FL, USA.
Taught Physics students MATLAB/Python programming and it’s relationship with BME simulations.

Technical Skills

Operating Systems: Windows / Linux

General Software: MS Office, Adobe Photoshop, Adobe Illustrator, Adobe Lightroom, Adobe InDesign, Publisher

Programming Languages: Python, JavaScript, Processing

Markup/Formatting Languages: HTML, CSS, Markdown

Scientific Computation and Simulation Packages: MATLAB, SIMULINK, COMSOL, ANSYS, LS-DYNA

CAD Modeling Software: SolidWorks, SpaceClaim, Blender

MATLAB Toolboxes: Neural Network, Image Processing, Data Acquisition, Computer Vision, Curve Fitting

Languages

Native: English, Urdu

Basic: Hindi


Last updated: July 2024